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Tag Archives: DePuy Spine

The Evolving Role of Bone-Graft Substitutes

It is estimated that more than 500,000 bone-grafting procedures are performed annually in the United States, with approximately half of these procedures related to spine fusion. These numbers easily double on a global basis and indicate a shortage in the availability of musculoskeletal donor tissue traditionally used in these reconstructions. This reality has stimulated a proliferation of corporate interest in supplying what is seen as a growing market in bone replacement materials. These graft alternatives are subjected to varying degrees of regulatory scrutiny, and thus their true safety and effectiveness in patients may not be know prior to their use by orthopaedic surgeons. It is thus important to gain insight into this emerging class of bone-substitute alternatives.

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Bone Graft Substitutes: Facts, Fictions & Applications

It is estimated that more than 500,000 bone-grafting procedures are performed annually in the United States, with approximately half of these procedures related to spine fusion. These numbers easily double on a global basis and indicate a shortage in the availability of musculoskeletal donor tissue traditionally used in these reconstructions. This reality has stimulated a proliferation of corporate interest in supplying what is seen as a growing market in bone replacement materials. These graft alternatives are subjected to varying degrees of regulatory scrutiny, and thus their true safety and effectiveness in patients may not be know prior to their use by orthopaedic surgeons. It is thus important to gain insight into this emerging class of bone-substitute alternatives.

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Bone Graft Substitutes: Facts, Fictions & Applications

It is estimated that more than 500,000 bone-grafting procedures are performed annually in the United States, with approximately half of these procedures related to spine fusion. These numbers easily double on a global basis and indicate a shortage in the availability of musculoskeletal donor tissue traditionally used in these reconstructions. This reality has stimulated a proliferation of corporate interest in supplying what is seen as a growing market in bone replacement materials. These graft alternatives are subjected to varying degrees of regulatory scrutiny, and thus their true safety and effectiveness in patients may not be know prior to their use by orthopaedic surgeons. It is thus important to gain insight into this emerging class of bone-substitute alternatives.

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The Current State of Cervical and Lumbar Spinal Disc Arthroplasty

The growth of spinal implant and orthobiologic technologies over the last several years is increasing in tempo and fast approaching the US hip and knee markets in annual dollar sales. During this time, a number of start-up and established medical device manufacturers have focused increasing resources on solutions for spinal problems. The role of the orthopaedic and neurosurgeon in these enterprises as inventor, owner, and user has contributed to this march of progress. This handout describes a small (<1%), but increasingly visible, aspect of these advancing technologies, that of artificial disc replacement.

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